I'm pretty new to the show, but one in particular that I remember was from 12/5/2012. It was towards the end of the show and some guy kept trying to talk politics and Tom wasn't having it, but the guy kept going until Tom screamed at the top of his lungs to get him to shut up. It caught me really off guard because I hadn't been listening to the show for more than a week or so. I can't recall who it was (he had a really soft and shaky voice) and I haven't listened to the episode since, but that one sticks out the most.