How about the Enzyte commercial with that guy "Bob" who smiles like an insane mannequin. It can follow the arc of his life, pre and post Enzyte. At the beginning he's just your ordinary anal-rententive creep with an abysmally unsatisfying marriage, but then Enzyte gives him a perpetual boner. His sex life at home heats up, and then his enhancment starts making him more confident at the work place. He gets a promotion, and other women take a lot of notice of him. He inevitably caves and sleeps with someone from the office. His wife finds out and things get sticky. She threatens to leave him, but she can't leave that boner, so their life takes a turn to a dark/abusive/polygamous place. Basically it becomes Big Love meets, I don't know, Kinski or something. His boner pushes him into ever-more escalating and exotic sexual encounters and ever-more complex repurcussions.