I already said it in the chat, but Stephen in Chicago's laugh is a never-mentioned and underrated Best Show strength. It gets me every time, and it's always a surprise.
I like a lot of the semi-regular callers. I've gotten to the point where it would be nice to hear from some of the old regulars every once in awhile as well. I'm listening back through the 2009 archive, so it seems like Fredericks is calling every week.