http://www.nytimes.com/2008/09/15/books/15wallace.htmlHis father said Sunday that Mr. Wallace had been taking medication for depression for 20 years and that it had allowed his son to be productive. It was something the writer didn’t discuss, though in interviews he gave a hint of his haunting angst.
In response to a question about what being an American was like for him at the end of the 20th century, he told the online magazine Salon in 1996 that there was something sad about it, but not as a reaction to the news or current events. “It’s more like a stomach-level sadness,” he said. “I see it in myself and my friends in different ways. It manifests itself as a kind of lostness.”
James Wallace said that last year his son had begun suffering side effects from the drugs and, at a doctor’s suggestion, had gone off the medication in June 2007. The depression returned, however, and no other treatment was successful. The elder Wallaces had seen their son in August, he said.
“He was being very heavily medicated,” he said. “He’d been in the hospital a couple of times over the summer and had undergone electro-convulsive therapy. Everything had been tried, and he just couldn’t stand it anymore.”