I'm curious about both Frost/Nixon and Milk but I also have my reservations. Milk, in particular, is a tough decision. On the plus side, I'm interested in the subject matter and I loved the Harvey Milk documentary from the 80s, but on the other side are the facts that I don't generally like biopics, I don't generally like Gus Van Sant films, and the fact that Penn (who I generally like as an actor) seems to be unnecessarily "gaying it up" (for lack of a better term) based on the clips in the previews.
The Wrestler is the one movie I'm unabashedly looking forward to.